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姓名:张晓华 出生年月:1965年9月 职称:教授、博士生导师 简历(从大学开始):$ `' v7 g2 @8 _2 H
1983/09-1987/07:山东大学生物系,动物学专业,学士9 ~7 ?. U1 W, u1 ]5 M
1987/09-1990/07:山东大学生物系,动物生理学专业,硕士* O/ A& d+ a9 y% @' F% f
1990/08-1994/10:山东省海洋药物研究所,助理研究员
1 U/ ]1 C6 r- b4 N8 \, I* {4 a1994/10-1998/04:青岛海洋大学海洋生物系,讲师、副教授
+ u$ d9 M% v" y+ u% E1998/04-2001/07:英国赫里奥特-瓦特大学生物系,微生物学专业,博士1 t. |: G1 i( R
2000/12-2003/11:英国牛津大学动物学系,博士后% v. d. i/ z6 `6 g0 f& p8 ?' M
2003/11-2004/06:英国剑桥大学遗传系,博士后, ?5 f; h# x( ?& _1 y8 n
2004/07-至今: 中国海洋大学海洋生物系,副教授、教授3 d/ a1 {3 T4 l! z- W8 E$ }9 O
研究方向:海洋微生物学、海洋水产养殖动物病原学 最近课题: 2004.01-2006.12:主持国家自然科学基金课题“海洋弧菌中溶血素的研究”(项目号:30371119)。, R. y2 [' q+ |5 l( w" m
2005.01-2007.12:2004年入选教育部新世纪优秀人才支持计划(项目号:NCET-04-0645)。 2005.10-2007.9:教育部留学回国人员科研启动基金“海鱼对哈维氏弧菌感染条件下的差异表达基因研究”(项目号:2005383)。6 S3 Q' J, E) t: @) Z
2006.10-2010.12:国家重点基础研究发展计划(973)“重要海水养殖动物病害发生和免疫防治的基础研究”的子课题“鱼类病原弧菌致病基因与疾病发生”(项目号:2006CB101803),主要参加者。! e6 J3 D/ }+ C9 `) j2 I0 l: d( K
主要论文: 1. Sun, B., Zhang X.-H.*, Tang, X., Wang, S., Zhong, Y., Chen, J. and Austin, B. (2007) A particular single residue change in Vibrio harveyi hemolysin (VHH) results in the loss of phospholipase and hemolytic activities and pathogenicity to turbot (Scophthalmus maximus). Journal of Bacteriology 189, 2575-2579. (SCI, IF2005: 4.167)
; K: m. h$ m) T6 n: }9 s2. Jordan, E. M., Thompson, F. L., Zhang, X.-H., Li, Y., Vancanneyt, M., Kroppenstedt, R. M., Priest, F. G. and Austin, B. (2007) Sneathiella chinensis gen. nov., sp. nov., a novel marine alphaproteobacterium isolated from coastal sediment in Qingdao, China. International Journal of Systematic and Evolutionary Microbiology 57, 114-121. (SCI, IF2005: 2.744) z% O( Z+ L! k( q+ g" P3 `, m( S
3. Zhong, Y., Zhang, X.-H.*, Chen, J., Chi, Z., Sun, B., Li, Y. and Austin, B. (2006) Overexpression, purification, characterization and pathogenitiy of Vibrio harveyi haemolysin VHH. Infection and Immunity 74, 6001-6005. (SCI, IF2005: 3.933) H5 `" g q/ P2 n( a+ k- c
4. Pang, L. Zhang, X.-H.*, Zhong, Y., Chen, J., Y., Li and Austin, B. (2006) Identification of Vibrio harveyi using PCR amplification of the toxR gene. Letters of Applied Microbiology 43, 249-255. (SCI, IF2005: 1.440)
: W3 M" ?$ [ a" s9 m+ F5. Austin, B. and Zhang, X.-H. (2006) Vibrio harveyi: a significant pathogen of marine vertebrates and invertebrates. Letters of Applied Microbiology 43, 119-124. (SCI, IF2005: 1.440)
$ ^+ P, c& M9 L5 n6 n' C$ d$ f6. Zhang, X.-H. and Austin, B. (2005) Haemolysins in Vibrio species. Journal of Applied Microbiology 98, 1011-1019. (SCI, IF2005: 2.127)
( j2 L/ G0 H! q7 _. T7. Zhang, X.-H., Axton, J.M., Drinjákovic, J. , Lorenz, L., White-Cooper, H. and Renault, A.D. (2004). Spatial and temporal control of the gnu regulator of embryonic mitosis in Drosophila. Journal of Cell Science 117, 3571-3578. (SCI, IF2004: 7.250)0 x# Q9 Z3 n U3 a
8. Renault, A.D., Zhang, X.-H., Alphey, L.S., Frenz, L.M., Glover, D.M., Saunders, R.D.C. and Axton, J.M. (2003). giant nuclei is essential in the cell cycle transition from meiosis to mitosis. Development 130, 2997-3005. (SCI, IF2004: 7.149)- E3 ?; L# P1 E; ~
9. Zhang, X.-H., Meaden, P.G. and Austin, B. (2001) Duplication of hemolysin genes in a virulent isolate of Vibrio harveyi. Applied and Environmental Microbiology. 67, 3161-3167. (SCI, IF2004: 3.810)
" `/ b, c( n' a9 |10. Zhang, X.-H. and Austin, B. (2000) Pathogenicity of Vibrio harveyi to Salmonids. Journal of Fish Diseases 23, 93-102. (SCI, IF2004: 1.587)
, D3 |* r, X4 r" c0 A& X11. Xu, H.-S., Zhang, X.-H., Xu, B., Ji, W.-S., Yang, X.-S. and Ma, J.-K.. (1999) Detection of Vibrio parahaemolyticus in Penaeus chinensis using an indirect fluorescent antibody staining procedure. World Journal of Microbiology and Biotechnology. 15(2): 325-328. (SCI, IF2004: 0.478)9 }4 u( }* n# S! _
12.张晓华、徐怀恕、许兵、纪伟尚、韩茵、杨学宋、马建康;对虾弧菌病的间接荧光抗体诊断技术研究。海洋与湖沼,1997;28(6):47-53。
- l0 s6 y) o3 j7 z13.张晓华、P. Robertson、B. Austin、徐怀恕:弧菌标准菌株外膜蛋白的比较研究。微生物学报,1997;37(6):449-454。
7 q+ L, w3 \! O14. 张晓华、P. Robertson、冯娟、纪伟尚、徐怀恕、B. Austin:中国对虾育苗池水中哈维氏弧菌的检测。青岛海洋大学学报,1998;28(1):70-74。
! a' G" c: c- I) ^15. 张晓华、廖绍安、李筠、纪伟尚、 徐怀恕:海湾扇贝病原菌(飘浮弧菌)的研究。青岛海洋大学学报,1998;28 (3):426-432。% w$ w' @) {7 y1 \- d
16. 张晓华、P. Robertson、B. Austin、徐怀恕:检测海洋弧菌的间接酶联免疫吸附试验研究。青岛海洋大学学报,1997;27(3):326-332。, U8 y) _+ y$ d9 b: h3 J
17. 张晓华、P. Robertson、B. Austin、徐怀恕:副溶血弧菌的外膜蛋白及其抗原性研究。中国水产科学,1997;4(4):54-58。7 {( G% m' Q" M! _0 e+ D0 p" u
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